Radwa Eladwy

Harnessing the power of gut microbiota for anticancer therapy: a continuum of gut microbiota and cancer

Recently, the gut microbiota has been investigated for its pivotal roles in pathogens protection and regulating metabolic, endocrine, and immune functions. In previous studies, the gut microbial metabolites (GMMs) have shown to improve gut and metabolic health by modulating the gut microbial composition.

This PhD project will investigate GMMs in vitro for their anticancer activity, attributing molecular actions and potential synergy. In addition, to the synergistic combinations of GMMs with standard immunotherapeutic or chemotherapeutic drugs against cancer cell lines will also be assessed. Findings from this study could help to evaluate the potential preventive/therapeutic anticancer activity of GMMs.

Supervisors:

Dr Deep Jyoti Bhuyan, Professor Dennis Chang, Professor Chun Guang Li