Dongzheng Liu
Study on Frontier Technologies and Applications in Plant-Derived Extracellular Vesicles
Extracellular vesicles (EVs) play a crucial role within biological systems, acting as key mediators of intercellular communication by transferring proteins, lipids, RNA, and other biomolecules, essential for maintaining normal physiological functions of the organism. While the functions and mechanisms of extracellular vesicles from animal and human sources have been extensively studied, including their potential roles in disease treatment and diagnosis, research on plant-derived extracellular vesicles is still limited. This project aims to investigate Australia's native plant-derived EVs using cutting-edge technologies and understand their properties and potential biomedical applications.
Dongzheng's PhD project is dedicated to exploring plant-derived EVs’ extraction, purification, and characterization, as well as their biological activities, with a particular interest in their potential effects and mechanisms in humans. Additionally, through RNA sequencing and omics analyses, the research aims to delve into the functions and potential applications of these plant-derived extracellular vesicles in drug development and general healthcare applications.
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